![Generation of Ugt1 knock-in mice. A) Targeted disruption of the mouse... | Download Scientific Diagram Generation of Ugt1 knock-in mice. A) Targeted disruption of the mouse... | Download Scientific Diagram](https://www.researchgate.net/publication/51807038/figure/fig1/AS:341690935201800@1458476875825/Generation-of-Ugt1-knock-in-mice-A-Targeted-disruption-of-the-mouse-Ugt1-locus-Maps-of.png)
Generation of Ugt1 knock-in mice. A) Targeted disruption of the mouse... | Download Scientific Diagram
![IJMS | Free Full-Text | Activation of Alternative Bilirubin Clearance Pathways Partially Reduces Hyperbilirubinemia in a Mouse Model Lacking Functional Ugt1a1 Activity IJMS | Free Full-Text | Activation of Alternative Bilirubin Clearance Pathways Partially Reduces Hyperbilirubinemia in a Mouse Model Lacking Functional Ugt1a1 Activity](https://www.mdpi.com/ijms/ijms-23-10703/article_deploy/html/images/ijms-23-10703-g001.png)
IJMS | Free Full-Text | Activation of Alternative Bilirubin Clearance Pathways Partially Reduces Hyperbilirubinemia in a Mouse Model Lacking Functional Ugt1a1 Activity
![Reduced Expression of UGT1A1 in Intestines of Humanized UGT1 Mice via Inactivation of NF-κB Leads to Hyperbilirubinemia - Gastroenterology Reduced Expression of UGT1A1 in Intestines of Humanized UGT1 Mice via Inactivation of NF-κB Leads to Hyperbilirubinemia - Gastroenterology](https://www.gastrojournal.org/cms/asset/da925d2e-0fe9-47f6-8aec-08ef5db58326/gr1.jpg)
Reduced Expression of UGT1A1 in Intestines of Humanized UGT1 Mice via Inactivation of NF-κB Leads to Hyperbilirubinemia - Gastroenterology
![Recent progress and challenges in screening and characterization of UGT1A1 inhibitors - ScienceDirect Recent progress and challenges in screening and characterization of UGT1A1 inhibitors - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2211383518304386-fx1.jpg)
Recent progress and challenges in screening and characterization of UGT1A1 inhibitors - ScienceDirect
![Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression | British Journal of Cancer Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression | British Journal of Cancer](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41416-019-0722-0/MediaObjects/41416_2019_722_Fig1_HTML.png)
Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression | British Journal of Cancer
![Humanized UGT1 Mice, Regulation of UGT1A1, and the Role of the Intestinal Tract in Neonatal Hyperbilirubinemia and Breast Milk-Induced Jaundice | Drug Metabolism & Disposition Humanized UGT1 Mice, Regulation of UGT1A1, and the Role of the Intestinal Tract in Neonatal Hyperbilirubinemia and Breast Milk-Induced Jaundice | Drug Metabolism & Disposition](https://dmd.aspetjournals.org/content/dmd/46/11/1745/F4.large.jpg)
Humanized UGT1 Mice, Regulation of UGT1A1, and the Role of the Intestinal Tract in Neonatal Hyperbilirubinemia and Breast Milk-Induced Jaundice | Drug Metabolism & Disposition
![IJMS | Free Full-Text | Activation of Alternative Bilirubin Clearance Pathways Partially Reduces Hyperbilirubinemia in a Mouse Model Lacking Functional Ugt1a1 Activity IJMS | Free Full-Text | Activation of Alternative Bilirubin Clearance Pathways Partially Reduces Hyperbilirubinemia in a Mouse Model Lacking Functional Ugt1a1 Activity](https://www.mdpi.com/ijms/ijms-23-10703/article_deploy/html/images/ijms-23-10703-g002.png)
IJMS | Free Full-Text | Activation of Alternative Bilirubin Clearance Pathways Partially Reduces Hyperbilirubinemia in a Mouse Model Lacking Functional Ugt1a1 Activity
![Gene structures of human UGT1 and UGT2. (A) Human UGT1 gene contains... | Download Scientific Diagram Gene structures of human UGT1 and UGT2. (A) Human UGT1 gene contains... | Download Scientific Diagram](https://www.researchgate.net/publication/309394071/figure/fig2/AS:420695524823040@1477313037109/Gene-structures-of-human-UGT1-and-UGT2-A-Human-UGT1-gene-contains-multiple-exon-1s-and.png)
Gene structures of human UGT1 and UGT2. (A) Human UGT1 gene contains... | Download Scientific Diagram
![Adult Ugt1 −/− animals have an upregulated level of blood and tissue... | Download Scientific Diagram Adult Ugt1 −/− animals have an upregulated level of blood and tissue... | Download Scientific Diagram](https://www.researchgate.net/publication/363816760/figure/fig1/AS:11431281086998348@1664429524187/Adult-Ugt1--animals-have-an-upregulated-level-of-blood-and-tissue-bilirubin-A.png)
Adult Ugt1 −/− animals have an upregulated level of blood and tissue... | Download Scientific Diagram
![A) Scheme of the TALEN reporter plasmids and strategy. The Ugt1 exon 4... | Download Scientific Diagram A) Scheme of the TALEN reporter plasmids and strategy. The Ugt1 exon 4... | Download Scientific Diagram](https://www.researchgate.net/publication/264798785/figure/fig2/AS:213926290694146@1428015410328/A-Scheme-of-the-TALEN-reporter-plasmids-and-strategy-The-Ugt1-exon-4-and-flanking.png)
A) Scheme of the TALEN reporter plasmids and strategy. The Ugt1 exon 4... | Download Scientific Diagram
![Humanized UGT1 Mice, Regulation of UGT1A1, and the Role of the Intestinal Tract in Neonatal Hyperbilirubinemia and Breast Milk-Induced Jaundice | Drug Metabolism & Disposition Humanized UGT1 Mice, Regulation of UGT1A1, and the Role of the Intestinal Tract in Neonatal Hyperbilirubinemia and Breast Milk-Induced Jaundice | Drug Metabolism & Disposition](https://dmd.aspetjournals.org/content/dmd/46/11/1745/F1.large.jpg)
Humanized UGT1 Mice, Regulation of UGT1A1, and the Role of the Intestinal Tract in Neonatal Hyperbilirubinemia and Breast Milk-Induced Jaundice | Drug Metabolism & Disposition
![Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransferase 1 (UGT1) locus | PNAS Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransferase 1 (UGT1) locus | PNAS](https://www.pnas.org/cms/10.1073/pnas.0913290107/asset/f95218c4-6cf7-4a74-a5fe-7225d4efcec5/assets/graphic/pnas.0913290107fig06.jpeg)
Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransferase 1 (UGT1) locus | PNAS
![Expression of UGT1A1 in neonatal liver and small-intestine tissues from... | Download Scientific Diagram Expression of UGT1A1 in neonatal liver and small-intestine tissues from... | Download Scientific Diagram](https://www.researchgate.net/publication/41656837/figure/fig4/AS:360600371777538@1462985236114/Expression-of-UGT1A1-in-neonatal-liver-and-small-intestine-tissues-from-humanized-UGT1.png)